Loss of miR-449a in ERG-associated prostate cancer promotes the invasive phenotype by inducing SIRT1

Epigenetic regulation by SIRT1, a multifaceted NAD(+)-dependent protein deacetylase, is one of the most common factors modulating cellular processes in a broad range of diseases, including prostate cancer (CaP). SIRT1 is over-expressed in CaP cells, however the associated mechanism is not well under...

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Vydáno v:Oncotarget
Hlavní autoři: Kumar, Parameet, Sharad, Shashwat, Petrovics, Gyorgy, Mohamed, Ahmed, Dobi, Albert, Sreenath, Taduru L., Srivastava, Shiv, Biswas, Roopa
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2016
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5008401/
https://ncbi.nlm.nih.gov/pubmed/26988912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8061
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