Association of HMGCR polymorphism with late-onset Alzheimer's disease in Han Chinese

The 3-hydroxy-3-methylglutaryl-CoA reductase (HMGCR) acts as a potential genetic modifier for Alzheimer's disease (AD). Previous reports identified that HMGCR rs3846662 polymorphism is associated with biosynthesis of cholesterol in AD pathology. In order to assess the involvement of the HMGCR p...

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Bibliographic Details
Published in:Oncotarget
Main Authors: Chang, Xiao-Long, Tan, Lin, Tan, Meng-Shan, Wang, Hui-Fu, Tan, Chen-Chen, Zhang, Wei, Zheng, Zhan-Jie, Kong, Ling-Li, Wang, Zi-Xuan, Jiang, Teng, Yu, Jin-Tai, Tan, Lan
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2016
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5008397/
https://ncbi.nlm.nih.gov/pubmed/27009838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8176
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