Association of HMGCR polymorphism with late-onset Alzheimer's disease in Han Chinese

The 3-hydroxy-3-methylglutaryl-CoA reductase (HMGCR) acts as a potential genetic modifier for Alzheimer's disease (AD). Previous reports identified that HMGCR rs3846662 polymorphism is associated with biosynthesis of cholesterol in AD pathology. In order to assess the involvement of the HMGCR p...

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Pubblicato in:Oncotarget
Autori principali: Chang, Xiao-Long, Tan, Lin, Tan, Meng-Shan, Wang, Hui-Fu, Tan, Chen-Chen, Zhang, Wei, Zheng, Zhan-Jie, Kong, Ling-Li, Wang, Zi-Xuan, Jiang, Teng, Yu, Jin-Tai, Tan, Lan
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2016
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5008397/
https://ncbi.nlm.nih.gov/pubmed/27009838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8176
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