Association of HMGCR polymorphism with late-onset Alzheimer's disease in Han Chinese

The 3-hydroxy-3-methylglutaryl-CoA reductase (HMGCR) acts as a potential genetic modifier for Alzheimer's disease (AD). Previous reports identified that HMGCR rs3846662 polymorphism is associated with biosynthesis of cholesterol in AD pathology. In order to assess the involvement of the HMGCR p...

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Bibliographische Detailangaben
Veröffentlicht in:Oncotarget
Hauptverfasser: Chang, Xiao-Long, Tan, Lin, Tan, Meng-Shan, Wang, Hui-Fu, Tan, Chen-Chen, Zhang, Wei, Zheng, Zhan-Jie, Kong, Ling-Li, Wang, Zi-Xuan, Jiang, Teng, Yu, Jin-Tai, Tan, Lan
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2016
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5008397/
https://ncbi.nlm.nih.gov/pubmed/27009838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8176
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