Association of HMGCR polymorphism with late-onset Alzheimer's disease in Han Chinese

The 3-hydroxy-3-methylglutaryl-CoA reductase (HMGCR) acts as a potential genetic modifier for Alzheimer's disease (AD). Previous reports identified that HMGCR rs3846662 polymorphism is associated with biosynthesis of cholesterol in AD pathology. In order to assess the involvement of the HMGCR p...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Chang, Xiao-Long, Tan, Lin, Tan, Meng-Shan, Wang, Hui-Fu, Tan, Chen-Chen, Zhang, Wei, Zheng, Zhan-Jie, Kong, Ling-Li, Wang, Zi-Xuan, Jiang, Teng, Yu, Jin-Tai, Tan, Lan
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5008397/
https://ncbi.nlm.nih.gov/pubmed/27009838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8176
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