Cancer-associated S100P protein binds and inactivates p53, permits therapy-induced senescence and supports chemoresistance

S100P belongs to the S100 family of calcium-binding proteins regulating diverse cellular processes. Certain S100 family members (S100A4 and S100B) are associated with cancer and used as biomarkers of metastatic phenotype. Also S100P is abnormally expressed in tumors and implicated in migration-invas...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Gibadulinova, Adriana, Pastorek, Michal, Filipcik, Pavel, Radvak, Peter, Csaderova, Lucia, Vojtesek, Borivoj, Pastorekova, Silvia
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5008377/
https://ncbi.nlm.nih.gov/pubmed/26967060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7999
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