Distinguishing epigenetic features of preneoplastic testis tissues adjacent to seminomas and nonseminomas

PIWI pathway proteins are expressed during spermatogenesis where they play a key role in germ cell development. Epigenetic loss of PIWI proteins expression was previously demonstrated in testicular germ cell tumors (TGCTs), implying their involvement in TGCT development. In this work, apart from stu...

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Détails bibliographiques
Publié dans:Oncotarget
Auteurs principaux: Gainetdinov, Ildar V., Kondratieva, Sofia A., Skvortsova, Yulia V., Zinovyeva, Marina V., Stukacheva, Elena A., Klimov, Alexey, Tryakin, Alexey A., Azhikina, Tatyana L.
Format: Artigo
Langue:Inglês
Publié: Impact Journals LLC 2016
Sujets:
Research Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5008371/
https://ncbi.nlm.nih.gov/pubmed/26843623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7074
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