Modulation of chemokines in the tumor microenvironment enhances oncolytic virotherapy for colorectal cancer

An oncolytic poxvirus such as vvDD-CXCL11 can generate potent systemic antitumor immunity as well as targeted oncolysis, yet the antitumor effect is limited probably due to limited homing to and suppressed activity of tumor-specific adaptive immune cells in the tumor microenvironment (TME). We reaso...

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Dettagli Bibliografici
Pubblicato in:Oncotarget
Autori principali: Francis, Lily, Guo, Zong Sheng, Liu, Zuqiang, Ravindranathan, Roshni, Urban, Julie A., Sathaiah, Magesh, Magge, Deepa, Kalinski, Pawel, Bartlett, David L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2016
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5008353/
https://ncbi.nlm.nih.gov/pubmed/26956047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7907
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