Infection of Common Marmosets with GB Virus B Chimeric Virus Encoding the Major Nonstructural Proteins NS2 to NS4A of Hepatitis C Virus

A lack of immunocompetent-small-primate models has been an obstacle for developing hepatitis C virus (HCV) vaccines and affordable antiviral drugs. In this study, HCV/GB virus B (GBV-B) chimeric virus carrying the major nonstructural proteins NS2 to NS4A (HCV NS2 to -4A chimera) was produced and use...

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Vydáno v:J Virol
Hlavní autoři: Zhu, Shaomei, Li, Tingting, Liu, Bochao, Xu, Yuxia, Sun, Yachun, Wang, Yilin, Wang, Yuanzhan, Shuai, Lifang, Chen, Zixuan, Allain, Jean-Pierre, Li, Chengyao
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2016
Témata:
Pathogenesis and Immunity
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5008089/
https://ncbi.nlm.nih.gov/pubmed/27384651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02653-15
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