Lack of Adaptation of Chimeric GB Virus B/Hepatitis C Virus in the Marmoset Model: Possible Effects of Bottleneck

Approximately 3% of the world population is chronically infected with hepatitis C virus (HCV). GB virus B (GBV-B), a surrogate model for HCV, causes hepatitis in tamarins and is the virus phylogenetically most closely related to HCV. Previously we described a chimeric GBV-B containing an HCV insert...

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Détails bibliographiques
Auteurs principaux: Weatherford, Trudie, Chavez, Deborah, Brasky, Kathleen M., Lemon, Stanley M., Martin, Annette, Lanford, Robert E.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 2009
Sujets:
Genetic Diversity and Evolution
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2715777/
https://ncbi.nlm.nih.gov/pubmed/19474092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00032-09
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