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The Role of the p53 Protein in Stem-Cell Biology and Epigenetic Regulation
The p53 protein plays a passive and an active role in stem cells. The transcriptional activities of p53 for cell-cycle arrest and DNA repair are largely turned off in stem cells, but there is some indication that long-term stem-cell viability may require other p53-regulated functions. When p53 is ac...
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| Publicado en: | Cold Spring Harb Perspect Med |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Cold Spring Harbor Laboratory Press
2016
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5008064/ https://ncbi.nlm.nih.gov/pubmed/27352800 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a026153 |
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