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The Role of the p53 Protein in Stem-Cell Biology and Epigenetic Regulation

The p53 protein plays a passive and an active role in stem cells. The transcriptional activities of p53 for cell-cycle arrest and DNA repair are largely turned off in stem cells, but there is some indication that long-term stem-cell viability may require other p53-regulated functions. When p53 is ac...

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Bibliografische gegevens
Gepubliceerd in:Cold Spring Harb Perspect Med
Hoofdauteurs: Levine, Arnold J., Puzio-Kuter, Anna M., Chan, Chang S., Hainaut, Pierre
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Cold Spring Harbor Laboratory Press 2016
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5008064/
https://ncbi.nlm.nih.gov/pubmed/27352800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a026153
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