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Stromal CCR6 drives tumor growth in a murine transplantable colon cancer through recruitment of tumor-promoting macrophages

Interactions between the inflammatory chemokine CCL20 and its receptor CCR6 have been implicated in promoting colon cancer; however, the mechanisms behind this effect are poorly understood. We have previously demonstrated that deficiency of CCR6 is associated with decreased tumor macrophage accumula...

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Detalhes bibliográficos
Publicado no:Oncoimmunology
Main Authors: Nandi, Bisweswar, Shapiro, Mia, Samur, Mehmet K., Pai, Christine, Frank, Natasha Y., Yoon, Charles, Prabhala, Rao H., Munshi, Nikhil C., Gold, Jason S.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5007974/
https://ncbi.nlm.nih.gov/pubmed/27622061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2016.1189052
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