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TARP vaccination is associated with slowing in PSA velocity and decreasing tumor growth rates in patients with Stage D0 prostate cancer

T-cell receptor alternate reading frame protein (TARP) is a 58-residue protein over-expressed in prostate and breast cancer. We investigated TARP peptide vaccination's impact on the rise in PSA (expressed as Slope Log(PSA) or PSA Doubling Time (PSADT)), validated tumor growth measures, and tumo...

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Vydáno v:Oncoimmunology
Hlavní autoři: Wood, Lauren V., Fojo, Antonio, Roberson, Brenda D., Hughes, Meghan S. B., Dahut, William, Gulley, James L., Madan, Ravi A., Arlen, Philip M., Sabatino, Marianna, Stroncek, David F., Castiello, Luciano, Trepel, Jane B., Lee, Min-Jung, Parnes, Howard L., Steinberg, Seth M., Terabe, Masaki, Wilkerson, Julia, Pastan, Ira, Berzofsky, Jay A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5007958/
https://ncbi.nlm.nih.gov/pubmed/27622067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2016.1197459
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