Conditional Ablation of Progesterone Receptor Membrane Component 1 Results in Subfertility in the Female and Development of Endometrial Cysts

Progesterone (P4) is essential for female fertility. The objective of this study was to evaluate the functional requirement of the nonclassical P4 receptor (PGR), PGR membrane component 1, in regulating female fertility. To achieve this goal, the Pgrmc1 gene was floxed by insertion of loxP sites on...

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Bibliografiske detaljer
Udgivet i:Endocrinology
Main Authors: McCallum, Melissa L., Pru, Cindy A., Niikura, Yuichi, Yee, Siu-Pok, Lydon, John P., Peluso, John J., Pru, James K.
Format: Artigo
Sprog:Inglês
Udgivet: Endocrine Society 2016
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5007897/
https://ncbi.nlm.nih.gov/pubmed/27309940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2016-1081
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