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Modification of tumor cell exosome content by transfection with wt-p53 and microRNA-125b expressing plasmid DNA and its effect on macrophage polarization

Exosomes are responsible for intercellular communication between tumor cells and others in the tumor microenvironment. These microvesicles promote oncogensis and can support towards metastasis by promoting a pro-tumorogenic environment. Modifying the exosomal content and exosome delivery are emergin...

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發表在:Oncogenesis
Main Authors: Trivedi, M, Talekar, M, Shah, P, Ouyang, Q, Amiji, M
格式: Artigo
語言:Inglês
出版: Nature Publishing Group 2016
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5007827/
https://ncbi.nlm.nih.gov/pubmed/27500388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/oncsis.2016.52
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