Adverse Geriatric Outcomes Secondary to Polypharmacy in a Mouse Model: The Influence of Aging

We aimed to develop a mouse model of polypharmacy, primarily to establish whether short-term exposure to polypharmacy causes adverse geriatric outcomes. We also investigated whether old age increased susceptibility to any adverse geriatric outcomes of polypharmacy. Young (n = 10) and old (n = 21) ma...

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Détails bibliographiques
Publié dans:J Gerontol A Biol Sci Med Sci
Auteurs principaux: Huizer-Pajkos, Aniko, Kane, Alice E., Howlett, Susan E., Mach, John, Mitchell, Sarah J., de Cabo, Rafael, Le Couteur, David G., Hilmer, Sarah N.
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2016
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Original Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5007735/
https://ncbi.nlm.nih.gov/pubmed/25940962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gerona/glv046
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