The BR domain of PsrP interacts with extracellular DNA to promote bacterial aggregation; structural insights into pneumococcal biofilm formation

The major human pathogen Streptococcus pneumoniae is a leading cause of disease and death worldwide. Pneumococcal biofilm formation within the nasopharynx leads to long-term colonization and persistence within the host. We have previously demonstrated that the capsular surface-associated pneumococca...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Schulte, Tim, Mikaelsson, Cecilia, Beaussart, Audrey, Kikhney, Alexey, Deshmukh, Maya, Wolniak, Sebastian, Pathak, Anuj, Ebel, Christine, Löfling, Jonas, Fogolari, Federico, Henriques-Normark, Birgitta, Dufrêne, Yves F., Svergun, Dmitri, Nygren, Per-Åke, Achour, Adnane
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5007671/
https://ncbi.nlm.nih.gov/pubmed/27582320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep32371
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