Different receptor mechanisms mediate the pyrogenic and behavioral effects of interleukin 1.

Interleukin 1 (IL-1) is a cytokine released during immune activation that mediates the host's response to infection and inflammation. Peripheral and central injections of IL-1 induce fever and sickness behavior, including decreased food motivation and reduced interest in social activities. To d...

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Bibliografiske detaljer
Main Authors: Kent, S, Bluthe, R M, Dantzer, R, Hardwick, A J, Kelley, K W, Rothwell, N J, Vannice, J L
Format: Artigo
Sprog:Inglês
Udgivet: 1992
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC50076/
https://ncbi.nlm.nih.gov/pubmed/1409612
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