Longitudinal in vivo MRI in a Huntington’s disease mouse model: Global atrophy in the absence of white matter microstructural damage

Huntington’s disease (HD) is a genetically-determined neurodegenerative disease. Characterising neuropathology in mouse models of HD is commonly restricted to cross-sectional ex vivo analyses, beset by tissue fixation issues. In vivo longitudinal magnetic resonance imaging (MRI) allows for disease p...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Steventon, Jessica J., Trueman, Rebecca C., Ma, Da, Yhnell, Emma, Bayram-Weston, Zubeyde, Modat, Marc, Cardoso, Jorge, Ourselin, Sebastian, Lythgoe, Mark, Stewart, Andrew, Rosser, Anne E., Jones, Derek K.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5007531/
https://ncbi.nlm.nih.gov/pubmed/27581950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep32423
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