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Protein oxidation associated with aging is reduced by dietary restriction of protein or calories.

The accumulation of unrepaired oxidative damage products may be a major factor in cellular aging. Both oxidative lesions in DNA and oxidatively damaged proteins have been shown to accumulate during aging. The accumulation of oxidized proteins in Fischer 344 rats was compared for animals consuming pr...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Autores principales: Youngman, L D, Park, J Y, Ames, B N
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 1992
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC50075/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1409611/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.19.9112
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