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Protein oxidation associated with aging is reduced by dietary restriction of protein or calories.

The accumulation of unrepaired oxidative damage products may be a major factor in cellular aging. Both oxidative lesions in DNA and oxidatively damaged proteins have been shown to accumulate during aging. The accumulation of oxidized proteins in Fischer 344 rats was compared for animals consuming pr...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Youngman, L D, Park, J Y, Ames, B N
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1992
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC50075/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1409611/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.19.9112
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