Nrf2 induces IL-17D to mediate tumor and virus surveillance

Cells undergoing xenobiotic or oxidative stress activate the transcription factor Nrf2, which initiates an intrinsic “stress surveillance” pathway. We recently found that the cytokine IL-17D effects a form of extrinsic stress surveillance by inducing antitumor immunity, but how IL-17D is regulated r...

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Bibliografske podrobnosti
izdano v:Cell Rep
Main Authors: Saddawi-Konefka, Robert, Seelige, Ruth, Gross, Emilie T.E., Levy, Eric, Searles, Stephen C., Washington, Allen, Santosa, Endi K., Liu, Beichen, O’Sullivan, Timothy E., Harismendy, Olivier, Bui, Jack D.
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5007173/
https://ncbi.nlm.nih.gov/pubmed/27545889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.07.075
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