Identification and editing of stem-like cells in methylcholanthrene-induced sarcomas

The cancer stem cell (CSC) paradigm posits that specific cells within a tumor, so-called CSC-like cells, have differing levels of tumorigenicity and chemoresistance. Original studies of CSCs identified them in human cancers and utilized mouse xenograft models to define the cancer initiating properti...

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Publicat a:Oncoimmunology
Autors principals: Gross, Emilie T. E., Peinado, Carlos D., Jung, Yujin, Han, Semi, Liu, Beichen, Santosa, Endi K., Bui, Jack D.
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2018
Matèries:
Original Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6287773/
https://ncbi.nlm.nih.gov/pubmed/30546937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2017.1404212
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