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Selective Sparing of Human Tregs by Pharmacologic Inhibitors of the Phosphatidylinositol 3-Kinase and MEK Pathways

Phosphatidylinositol 3-kinase (PI3K) and mitogen-activated protein kinase/extracellular signal-regulated (MEK) signaling are central to the survival and proliferation of many cell types. Multiple lines of investigation in murine models have shown that control of the PI3K pathway is particularly impo...

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Detalles Bibliográficos
Publicado en:Am J Transplant
Autores principales: Zwang, N. A., Zhang, R., Germana, S., Fan, M. Y., Hastings, W. D., Cao, A., Turka, L. A.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5007157/
https://ncbi.nlm.nih.gov/pubmed/27017850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ajt.13805
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