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Ciliary Entry of the Hedgehog Transcriptional Activator Gli2 Is Mediated by the Nuclear Import Machinery but Differs from Nuclear Transport in Being Imp-α/β1-Independent

Gli2 is the primary transcriptional activator of Hedgehog signalling in mammals. Upon stimulation of the pathway, Gli2 moves into the cilium before reaching the nucleus. However, the mechanisms underlying its entry into the cilium are not completely understood. Since several similarities have been r...

詳細記述

保存先:
書誌詳細
出版年:PLoS One
主要な著者: Torrado, Belén, Graña, Martín, Badano, José L., Irigoín, Florencia
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5007031/
https://ncbi.nlm.nih.gov/pubmed/27579771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0162033
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