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Anti-CD137 enhances anti-CD20 therapy of systemic B-cell lymphoma with altered immune homeostasis but negligible toxicity

Studies of sequential anti-CD137/anti-CD20 therapy have previously shown that the efficacy of anti-CD20 was heavily reliant upon anti-CD137; however, the exact mechanism of the anti-B-cell lymphoma efficacy, and whether this correlates with enhanced adverse effects or toxicity, had not been elucidat...

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Publicado en:Oncoimmunology
Autores principales: Souza-Fonseca-Guimaraes, Fernando, Blake, Stephen J., Makkouk, Amani, Chester, Cariad, Kohrt, Holbrook E., Smyth, Mark J.
Formato: Artigo
Lenguaje:Inglês
Publicado: Taylor & Francis 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5006917/
https://ncbi.nlm.nih.gov/pubmed/27622048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2016.1192740
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