Broad HIV-1 inhibition in vitro by vaccine-elicited CD8(+) T cells in African adults

We are developing a pan-clade HIV-1 T-cell vaccine HIVconsv, which could complement Env vaccines for prophylaxis and be a key to HIV cure. Our strategy focuses vaccine-elicited effector T-cells on functionally and structurally conserved regions (not full-length proteins and not only epitopes) of the...

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Veröffentlicht in:Mol Ther Methods Clin Dev
Hauptverfasser: Mutua, Gaudensia, Farah, Bashir, Langat, Robert, Indangasi, Jackton, Ogola, Simon, Onsembe, Brian, Kopycinski, Jakub T, Hayes, Peter, Borthwick, Nicola J, Ashraf, Ambreen, Dally, Len, Barin, Burc, Tillander, Annika, Gilmour, Jill, De Bont, Jan, Crook, Alison, Hannaman, Drew, Cox, Josephine H, Anzala, Omu, Fast, Patricia E, Reilly, Marie, Chinyenze, Kundai, Jaoko, Walter, Hanke, Tomáš, HIV-CORE 004 study group, the
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5006719/
https://ncbi.nlm.nih.gov/pubmed/27617268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mtm.2016.61
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