Astroglia acquires a toxic neuroinflammatory role in response to the cerebrospinal fluid from amyotrophic lateral sclerosis patients

BACKGROUND: Non-cell autonomous toxicity is one of the potential mechanisms implicated in the etiopathogenesis of amyotrophic lateral sclerosis (ALS). However, the exact role of glial cells in ALS pathology is yet to be fully understood. In a cellular model recapitulating the pathology of sporadic A...

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Detalhes bibliográficos
Publicado no:J Neuroinflammation
Main Authors: Mishra, Pooja-Shree, Dhull, Dinesh K., Nalini, A., Vijayalakshmi, K., Sathyaprabha, T. N., Alladi, Phalguni Anand, Raju, Trichur R.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5006495/
https://ncbi.nlm.nih.gov/pubmed/27578023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-016-0698-0
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