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Shortening Tuberculosis Treatment With Fluoroquinolones: Lost in Translation?

The disappointing recent failure of fluoroquinolone-containing regimens to shorten the duration of tuberculosis treatment in costly phase 3 trials has raised serious questions about the reliability of preclinical tuberculosis models, especially mice, and the current paradigm of regimen development....

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Detalhes bibliográficos
Publicado no:Clin Infect Dis
Main Authors: Lanoix, Jean-Philippe, Chaisson, Richard E., Nuermberger, Eric L.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5006403/
https://ncbi.nlm.nih.gov/pubmed/26527614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cid/civ911
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