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Inhibitory effect of NBL1 on PDGF-BB-induced human PASMC proliferation through blockade of PDGFβ-p38MAPK pathway

Pulmonary artery remodelling is a key feature in the pathological progress of pulmonary arterial hypertension (PAH). Moreover, excessive proliferation of pulmonary arterial smooth muscle cells (PASMCs) plays a critical role in the pathogenesis of pulmonary artery remodelling. Neuroblastoma suppresso...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Biosci Rep
Hauptverfasser: Cui, Chuanjue, Zhang, Hongliang, Guo, Lin-Na, Zhang, Xiaoling, Meng, Liukun, Pan, Xiangbin, Wei, Yingjie
Format: Artigo
Sprache:Inglês
Veröffentlicht: Portland Press Ltd. 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5006314/
https://ncbi.nlm.nih.gov/pubmed/27474499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20160199
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