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Protein backbone ensemble generation explores the local structural space of unseen natural homologs
Motivation: Mutations in homologous proteins affect changes in the backbone conformation that involve a complex interplay of forces which are difficult to predict. Protein design algorithms need to anticipate these backbone changes in order to accurately calculate the energy of the structure given a...
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Publicado no: | Bioinformatics |
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Main Authors: | , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Oxford University Press
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5006151/ https://ncbi.nlm.nih.gov/pubmed/26787668 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btw001 |
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