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Using Structure to Explore the Sequence Alignment Space of Remote Homologs

Protein structure modeling by homology requires an accurate sequence alignment between the query protein and its structural template. However, sequence alignment methods based on dynamic programming (DP) are typically unable to generate accurate alignments for remote sequence homologs, thus limiting...

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Podrobná bibliografie
Hlavní autoři: Kuziemko, Andrew, Honig, Barry, Petrey, Donald
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3188491/
https://ncbi.nlm.nih.gov/pubmed/21998567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1002175
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