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On the Accuracy of Homology Modeling and Sequence Alignment Methods Applied to Membrane Proteins

In this study, we investigate the extent to which techniques for homology modeling that were developed for water-soluble proteins are appropriate for membrane proteins as well. To this end we present an assessment of current strategies for homology modeling of membrane proteins and introduce a bench...

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Detalhes bibliográficos
Main Authors: Forrest, Lucy R., Tang, Christopher L., Honig, Barry
Formato: Artigo
Idioma:Inglês
Publicado em: Biophysical Society 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1483079/
https://ncbi.nlm.nih.gov/pubmed/16648166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.106.082313
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