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Targeted overexpression of mitochondrial catalase protects against cancer chemotherapy-induced skeletal muscle dysfunction
The loss of strength in combination with constant fatigue is a burden on cancer patients undergoing chemotherapy. Doxorubicin, a standard chemotherapy drug used in the clinic, causes skeletal muscle dysfunction and increases mitochondrial H(2)O(2). We hypothesized that the combined effect of cancer...
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| Publicado no: | Am J Physiol Endocrinol Metab |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5005971/ https://ncbi.nlm.nih.gov/pubmed/27329802 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00540.2015 |
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