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Increased levels of hyper-stable protein aggregates in plasma of older adults
Proteins that misfold into hyper-stable/degradation-resistant species during aging may accumulate and disrupt protein homeostasis (i.e., proteostasis), thereby posing a survival risk to any organism. Using the method diagonal two-dimensional (D2D) SDS-PAGE, which separates hyper-stable SDS-resistant...
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發表在: | Age (Dordr) |
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Main Authors: | , , , |
格式: | Artigo |
語言: | Inglês |
出版: |
Springer International Publishing
2016
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主題: | |
在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5005920/ https://ncbi.nlm.nih.gov/pubmed/27179971 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11357-016-9919-9 |
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