Common SIRT1 variants modify the effect of abdominal adipose tissue on aging-related lung function decline

Lung function is an independent predictor of mortality and serves as an aging marker in never smokers. The protein sirtuin-1 of gene SIRT1 has profound anti-inflammatory effects and regulates metabolic pathways. Its suggested longevity effects on lower organisms remain poorly studied in humans. In 1...

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Detalhes bibliográficos
Publicado no:Age (Dordr)
Main Authors: Curjuric, Ivan, Imboden, Medea, Bridevaux, Pierre-Olivier, Gerbase, Margaret W., Haun, Margot, Keidel, Dirk, Kumar, Ashish, Pons, Marco, Rochat, Thierry, Schikowski, Tamara, Schindler, Christian, von Eckardstein, Arnold, Kronenberg, Florian, Probst-Hensch, Nicole M.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5005914/
https://ncbi.nlm.nih.gov/pubmed/27125385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11357-016-9917-y
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