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An increased need for dietary cysteine in support of glutathione synthesis may underlie the increased risk for mortality associated with low protein intake in the elderly

Restricted dietary intakes of protein or essential amino acids tend to slow aging and boost lifespan in rodents, presumably because they downregulate IGF-I/Akt/mTORC1 signaling that acts as a pacesetter for aging and promotes cancer induction. A recent analysis of the National Health and Nutrition E...

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Detalhes bibliográficos
Publicado no:Age (Dordr)
Main Authors: McCarty, Mark F., DiNicolantonio, James J.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5005830/
https://ncbi.nlm.nih.gov/pubmed/26362762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11357-015-9823-8
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