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Amplified in Breast Cancer Regulates Transcription and Translation in Breast Cancer Cells
BACKGROUND: Control of mRNA translation is fundamentally altered in cancer. Insulin-like growth factor-I (IGF-I) signaling regulates key translation mediators to modulate protein synthesis (e.g. eIF4E, 4E-BP1, mTOR, and S6K1). Importantly the Amplified in Breast Cancer (AIB1) oncogene regulates tran...
Wedi'i Gadw mewn:
Cyhoeddwyd yn: | Neoplasia |
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Prif Awduron: | , , , , , |
Fformat: | Artigo |
Iaith: | Inglês |
Cyhoeddwyd: |
Neoplasia Press
2016
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Pynciau: | |
Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5005264/ https://ncbi.nlm.nih.gov/pubmed/26936396 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neo.2016.01.001 |
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