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Amplified in Breast Cancer Regulates Transcription and Translation in Breast Cancer Cells
Background: Control of mRNA translation is fundamentally altered in cancer. Insulin-like growth factor-I (IGF-I) signaling regulates key translation mediators to modulate protein synthesis (e.g. eIF4E, 4E-BP1, mTOR, and S6K1). Importantly the Amplified in Breast Cancer (AIB1) oncogene regulates tran...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2016-02-01
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| Colecção: | Neoplasia: An International Journal for Oncology Research |
| Acesso em linha: | http://www.sciencedirect.com/science/article/pii/S1476558616000026 |
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