A colitogenic memory CD4(+) T cell population mediates gastrointestinal graft-versus-host disease

Damage to the gastrointestinal tract is a major cause of morbidity and mortality in graft-versus-host disease (GVHD) and is attributable to T cell–mediated inflammation. In this work, we identified a unique CD4(+) T cell population that constitutively expresses the β(2) integrin CD11c and displays a...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Zhou, Vivian, Agle, Kimberle, Chen, Xiao, Beres, Amy, Komorowski, Richard, Belle, Ludovic, Taylor, Carolyn, Zhu, Fenlu, Haribhai, Dipica, Williams, Calvin B., Verbsky, James, Blumenschein, Wendy, Sadekova, Svetlana, Bowman, Eddie, Ballantyne, Christie, Weaver, Casey, Serody, David A., Vincent, Benjamin, Serody, Jonathan, Cua, Daniel J., Drobyski, William R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5004941/
https://ncbi.nlm.nih.gov/pubmed/27500496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI80874
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