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Staphylococcus aureus recruits Cdc42GAP through recycling endosomes and the exocyst to invade human endothelial cells

Activation and invasion of the vascular endothelium by Staphylococcus aureus is a major cause of sepsis and endocarditis. For endothelial cell invasion, S. aureus triggers actin polymerization through Cdc42, N-WASp (also known as WASL) and the Arp2/3 complex to assemble a phagocytic cup-like structu...

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Detalhes bibliográficos
Publicado no:J Cell Sci
Main Authors: Rauch, Liane, Hennings, Kirsten, Trasak, Claudia, Röder, Anja, Schröder, Barbara, Koch-Nolte, Friedrich, Rivera-Molina, Felix, Toomre, Derek, Aepfelbacher, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5004874/
https://ncbi.nlm.nih.gov/pubmed/27311480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.186213
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