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Exocyst structural changes associated with activation of tethering downstream of Rho/Cdc42 GTPases

The exocyst complex plays a critical role in determining both temporal and spatial dynamics of exocytic vesicle tethering and fusion with the plasma membrane. However, the mechanism by which the exocyst functions and how it is regulated remain poorly understood. Here we describe a novel biochemical...

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Vydáno v:J Cell Biol
Hlavní autoři: Rossi, Guendalina, Lepore, Dante, Kenner, Lillian, Czuchra, Alexander B., Plooster, Melissa, Frost, Adam, Munson, Mary, Brennwald, Patrick
Médium: Artigo
Jazyk:Inglês
Vydáno: Rockefeller University Press 2020
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7041683/
https://ncbi.nlm.nih.gov/pubmed/31904797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201904161
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