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Transduction of primary human hepatocytes with amphotropic and xenotropic retroviral vectors.

Experiments in animal models suggest that it is feasible to consider hepatic gene therapy using a strategy in which hepatocytes would be isolated by partial hepatectomy, transduced with recombinant retroviral vectors containing genes of therapeutic importance, and then transplanted back into the pat...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Adams, R M, Soriano, H E, Wang, M, Darlington, G, Steffen, D, Ledley, F D
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1992
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC50048/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1329086/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.19.8981
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