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Chromosome 11q in sporadic colorectal carcinoma: patterns of allele loss and their significance for tumorigenesis.

AIMS: To analyse the frequency of loss of heterozygosity (allele loss, LOH) in a large sample of colorectal carcinomas using highly informative markers along chromosome 11q. METHODS: One hundred paired samples of colorectal cancer and normal tissue were genotyped at six microsatellite markers on chr...

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Publicat a:J Clin Pathol
Autors principals: Tomlinson, I P, Bodmer, W F
Format: Artigo
Idioma:Inglês
Publicat: BMJ Publishing Group 1996
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC500477/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8707952/
https://ncbi.nlm.nih.govhttps://doi.org/10.1136/jcp.49.5.386
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