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Chromosome 5 allele loss in familial and sporadic colorectal adenomas.

DNA extracted from familial and sporadic colorectal neoplasms was compared with constitutional DNA using a range of hypervariable locus specific probes to assess the extent of allele loss during conversion to malignancy. Chromosome 5 allele loss was observed in 23% of carcinoma samples, as previousl...

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Detalhes bibliográficos
Main Authors: Rees, M., Leigh, S. E., Delhanty, J. D., Jass, J. R.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 1989
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2247069/
https://ncbi.nlm.nih.gov/pubmed/2539177
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