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Mutation of the Dyslexia-Associated Gene Dcdc2 Enhances Glutamatergic Synaptic Transmission Between Layer 4 Neurons in Mouse Neocortex

Variants in DCDC2 have been associated with reading disability in humans, and targeted mutation of Dcdc2 in mice causes impairments in both learning and sensory processing. In this study, we sought to determine whether Dcdc2 mutation affects functional synaptic circuitry in neocortex. We found mutat...

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Detalhes bibliográficos
Publicado no:Cereb Cortex
Main Authors: Che, Alicia, Truong, Dongnhu T., Fitch, R. Holly, LoTurco, Joseph J.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5004750/
https://ncbi.nlm.nih.gov/pubmed/26250775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cercor/bhv168
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