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Mutation of the Dyslexia-Associated Gene Dcdc2 Enhances Glutamatergic Synaptic Transmission Between Layer 4 Neurons in Mouse Neocortex

Variants in DCDC2 have been associated with reading disability in humans, and targeted mutation of Dcdc2 in mice causes impairments in both learning and sensory processing. In this study, we sought to determine whether Dcdc2 mutation affects functional synaptic circuitry in neocortex. We found mutat...

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Bibliografiske detaljer
Udgivet i:Cereb Cortex
Main Authors: Che, Alicia, Truong, Dongnhu T., Fitch, R. Holly, LoTurco, Joseph J.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2016
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5004750/
https://ncbi.nlm.nih.gov/pubmed/26250775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cercor/bhv168
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