Mechanical Ventilation Augments Poly(I:C)-Induced Lung Injury via a WISP1-Integrin β3-Dependent Pathway in Mice

Mechanical ventilation can improve hypoxemia, but can also cause the so-called ventilator-induced lung injury (VILI). Polyinosinic:polycytidylic acid (poly(I:C)), an analogue of natural double-strand RNA virus, can induce lung inflammation. The purpose of this study was to determine whether moderate...

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Detalhes bibliográficos
Publicado no:Mol Med
Main Authors: Jin, Shuqing, Chen, Zhixia, Ding, Xibing, Zhao, Xiang, Jiang, Xi, Tong, Yao, Billiar, Timothy R, Li, Quan
Formato: Artigo
Idioma:Inglês
Publicado em: Feinstein Institute for Medical Research 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5004712/
https://ncbi.nlm.nih.gov/pubmed/26772774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2015.00233
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