Targeting highly expressed extracellular HSP90 in breast cancer stem cells inhibits tumor growth in vitro and in vivo

Breast cancer stem cells (BCSC) have been identified in breast carcinoma as CD44(+)/CD24(−/low) cells, which display tumorigenic activity and have the ability to self-renew, differentiate and metastasize. Previous studies showed that extracellular HSP90 (eHSP90) participates in the invasion and meta...

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Vydáno v:Cancer Biol Ther
Hlavní autoři: Stivarou, Theodora, Stellas, Dimitris, Vartzi, Georgia, Thomaidou, Dimitra, Patsavoudi, Evangelia
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2016
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Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5004692/
https://ncbi.nlm.nih.gov/pubmed/27259689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384047.2016.1195041
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