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Cell Surface Cdc37 Participates in Extracellular HSP90 Mediated Cancer Cell Invasion

Cdc37 is a 50 kDa molecular chaperone which targets intrinsically unstable protein kinases to the molecular chaperone HSP90. It is also an over-expressed oncoprotein that mediates carcinogenesis and maintenance of the malignant phenotype by stabilizing the compromised structures of mutant and/or ove...

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Bibliografiske detaljer
Main Authors: El Hamidieh, Avraam, Grammatikakis, Nicholas, Patsavoudi, Evangelia
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3422348/
https://ncbi.nlm.nih.gov/pubmed/22912728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0042722
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