Antitumor effect of pyrrolo-1,5-benzoxazepine-15 and its synergistic effect with Oxaliplatin and 5-FU in colorectal cancer cells

Some compounds of a series of novel pyrrolo-1,5-benzoxa(thia)zepine, a well-known group of tubulin targeting agents, display anti-tumor effects mainly inducing cell cycle arrest and apoptosis in several human cancer models. A member of this family, pyrrolo-1,5-benzoxazepine-15 (PBOX-15), has previou...

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Sparad:
Bibliografiska uppgifter
I publikationen:Cancer Biol Ther
Huvudupphovsmän: Fiore, Donatella, Proto, Maria Chiara, Pisanti, Simona, Picardi, Paola, Pagano Zottola, Antonio Christian, Butini, Stefania, Gemma, Sandra, Casagni, Alice, Laezza, Chiara, Vitale, Mario, Ligresti, Alessia, Di Marzo, Vincenzo, Zisterer, Daniela M., Nathwani, Seema, Williams, D. Clive, Campiani, Giuseppe, Gazzerro, Patrizia, Bifulco, Maurizio
Materialtyp: Artigo
Språk:Inglês
Publicerad: Taylor & Francis 2015
Ämnen:
Research Paper
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5004676/
https://ncbi.nlm.nih.gov/pubmed/26392056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384047.2015.1078028
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